Our long-term goal as a research group is to develop redox-neutral cycloaddition strategies for convergent access to highly functionalized motifs found within pharmaceuticals, natural products, and high-value materials. Our approaches focus on the design of atypical reaction partners that are at a high oxidation level (i.e., large degree of heteroatom incorporation and/or unsaturation) in order to avoid redox manipulations post cycloaddition. Consequently, our methods are typically inherently step economic (e.g., proceeding via cycloaddition/spontaneous aromatization), and require only mild reaction conditions (e.g., simply mixing of reaction partners, often without the need for additional reagents or temperature control). A significant challenge within this area is the development of methods that meet these requirements, while remaining operationally friendly, for highly unsaturated heteroatom-rich molecules often exhibit highly challenging stability profiles. Consequently, a major focus within our program is to develop methods that can be conducted without the need for specialized equipment and/or handling techniques.